Symbol
Name
ID

Gata3
GATA binding protein 3
MGI:95663

Phenotype annotations related to hematopoietic system

Darker colors indicate more annotations

Human Phenotypes	Abnormality of T cell physiology
Disease(s) Associated with GATA3	Abnormality of T cell physiology
hypoparathyroidism-deafness-renal disease syndrome

Mouse Phenotypes

increased T cell apoptosis

small thymus

decreased thymocyte number

abnormal definitive hematopoiesis

abnormal T cell differentiation

decreased double-negative T cell number

abnormal double-positive T cell morphology

decreased double-positive T cell number

arrested T cell differentiation

decreased eosinophil cell number

abnormal erythrocyte morphology

abnormal T cell subpopulation ratio

abnormal T cell number

increased T-helper 1 cell number

decreased T-helper 2 cell number

decreased CD4-positive, alpha-beta T cell number

abnormal CD8-positive, alpha-beta T cell number

decreased gamma-delta T cell number

decreased T cell number

abnormal CD4-positive, alpha beta T cell morphology

decreased IgE level

Availability

Mouse Genotype

Gata3^tm1Jeng/Gata3^tm1Jeng

Gata3^tm2Jeng/Gata3^tm2Jeng

Gata3^tm1Iho/Gata3^tm1Iho
Tg(Lck-cre)1Cwi/0 (conditional)

Gata3^tm1Iho/Gata3^tm1Iho
Tg(Cd4-cre)1Cwi/0 (conditional)

Gata3^tm1Iho/Gata3^tm1Iho
Il13^{tm1(YFP/cre)Lky}/Il13⁺ (conditional)

Gata3^tm1Jfz/Gata3^tm1Jfz
Tg(Cd4-cre)1Cwi/0 (conditional)

Gata3^tm1Jfz/Gata3^tm1Jfz
Tg(Tnfrsf4-cre)1Nik/0 (conditional)

Gata3^tm3Gsv/Gata3^tm3Gsv
Tg(KRT14-cre)8Brn/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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